The third edition of the World Duchenne Awareness day was focused on early diagnosis: identifying and communicating early signs of Duchenne in order to guarantee a good quality of life to the children. Delayed gross motor milestones, Gower’s sign, and delayed speech should raise a red flag and be followed up by a CK blood test as soon as possible. Early diagnosis of Duchenne can allow for timely access to genetic counseling, standards of care, and opportunities for clinical trials. It was asked to many families of different countries of the world to express why Early Diagnosis is so important for the DMD boys.